NATIONAL HEART, LUNG AND BLOOD INSTITUE
Hematology Branch
Clinical Trial



Protocol Number Title of Protocol Principal Investigator
RN's/Contact
Phone#
00-H-0049 A phase II study of antithymocyte globulin
and cyclosporine to treat the cytopenia of
myelodysplastic syndrome
J.Barrett Laura Wisch 301-402-0797
00-H-0167 Collection of liver tissue for virologic studies N.Young Olga Nunez 301-496-4462
00-H-0157 A randomized trial for the treatment of
replapsing aplastic anemia with
mycophenolate mefetil(MMF)
and cyclosporine (CSA)
N.Young Olga Nunez 301-496-4462
00-H-0156 A pilot study of phenylbutyrate,
dexamethasone and GM-CSF in refractory
or relapsed t(8;21) Acute Myeloid Leukemia
J. Barrett Sheila Phang 301-402-3595
00-H-0120 An epidemiological study of subjects with
immune thrombocytopenic purpura to
evaluate the relationship between platelet
counts, endogenous thrombopoietin levels,
endogenous anti-thrombopoietin antibodis,
and selected autoimmune markers
C.Dunbar Adeira Greene 301-496-3841
00-H-0064 A pilot study of the recombinant soluble
recombinant human tumor necrosis factor
receptor (p75)-Fc fusion protein in patients
with myelodysplastic syndrome
J.Maciejewski Laura Wisch 301-402-0797
00-H-0060 Leukapheresis of volunteers with sickle cell
trait to evaluate mobilization of stem cells
with granulocyte colony-stimulating factor
and stem cell collection and storage for
allogeneic transplantation
E.Kang Beth Link 301-402-3087
00-DK-0040 Effect of Hydroxyurea on the level of
ineffective erythropoiesis, transfusion
requirement, and fetal hemoglobin synthesis
in patients with Beta-Thalassemia Intermedia
G.Rodgers Beth Link 301-402-3087
00-H-0032 Treatment of aplastic anemia with combined
immunosuppression; ATG, CSA and MMF
N.Young Olga Nunez 301-496-4462
00-H-0029 A Pilot study of recombinant humanized
Anti-IL2 receptor antibody (Daclizumab) in
patients with moderate aplastic anemia,
pure red cell aplasia or amegakaryocytic
thrombocytopenia purpura
J.Maciejewski Olga Nunez 301-496-4462
00-H-0001 Non-myeloablative allogeneic peripheral
blood mobilized hematopoietic precursor
cell transplantation for chronic phase CML
R.Sloand Sheila Phang
Adeira Greene
301-402-3595
301-496-3841
99-H-0167 Low intensity non-myeloablative preparative
conditioning followed by transplantation of
genetically modified HLA-matched
peripheral blood hematopoietic precursor cells (PBPC) for hematologic malignancies
in HIV positive adults
J.Tisdale Sheila Phang 301-402-3595
99-H-0064 Exploratory study of non-myeloablative
allogeneic stem cell transplantation and
donor lymphocyte infusions for metastatic
neoplasms refractory to standard therapy.
R.Childs Rose Goodwin
Adeira Greene
301-402-3595
301-496-3841
99-H-0060 Collection of blood and stools samples in
patients with acute hepatitis
N.Young Olga Nunez 301-496-4462
99-H-0050 Non-myeloablative allogeneic peripheral
blood mobilized hematopoietic precursor
cell transplantation for hematologic
malignancies in high risk patients and in
patients with debilating hematologic diseases.
R.Childs Rose Goodwin 301-402-3595
99-H-0046 Peripheral blood mobilized hematological
precursor cell transplantation followed by T-cell
add back for hematological
malignancies - role of cyclosporine
J.Barrett Sheila Phang
Aderia Greene
Ginnie Mayo
301-402-3595
301-496-3841
301-402-5609
99-H-0037 Apheresis of family members of patients
undergoing allogeneic bone marrow
transplantation. A pre-clinical study of
selective depletion of donor lymphocytes
to prevent acute-graft-versus-host disease
J.Barrett Sheila Phang
Aderia Greene
Ginnie Mayo
301-402-3595
301-496-3841
301-402-5609
98-H-0154 Auto transplant for myeloma - G-CSF vs
SCF/G-CSF mobilization
C.Dunbar Adeira Greene 301-496-3841
98-H-0144 Treatment of diamond-blackfan anemia with
antithymocyte globulin and cyclosporine A
E.Kang Laura Wisch 301-402-0795
98-I-0104 Low intensity preparative regimen followed
by HLA-matched, mobilized peripheral blood
stem cell transplantation for chronic
granulomatous disease
M.Horrwitz Sheila Phang
Adeira Greene
301-402-3595
301-496-3841
98-H-0006 HLA-matched peripheral blood mobilized
hematopoietic progenitor cell transplantation
for metastatic melanoma followed by
allogeneic T-cell infusion as adoptive
immunotherapy
R.Childs Rose Goodwin
Adeira Greene
301-402-3595
301-496-3841
97-H-0202 Low intensity preparative regimen followed
by HLA-matched, peripheral blood mobilized
hematopoietic precursor cell transplantation
for hematologic malignancies in older adults
J.Barrett Sheila Phang
Adeira Greene
301-402-3595
301-496-3841
97-H-0196 HLA-matched peripheral blood mobilized
hematopoietic progenitor cell transplantation
for metastatic renal cell carcinoma followed
by allogeneic T-cell infusion as adoptive
immunotherapy
R.Childs Ginny Mayo 301-402-5609
97-H-0154 High-dose cyclophosphamide with CD34+
selected autologous hematopoietic cell
support for treatment of refractory chronic
autoimmune thrombocytopenia
C.Dunbar Adeira Greene 301-496-3841
97-H-0130 Collection of blood and bone marrow from
normal volunteers and patients for research
purposes
N.Young
97-H-0041 Screening protocol for patients with bone
marrow failure states, isolated or
multilineage cytopenias, or hematologic
malignancies
C.Dunbar
96-H-0049 Use of granulocyte colony stimulating factor
mobilized leukapheresis collections from
normal volunteers to develop improved
methods of stem cell and lymphocyte
selection for allogeneic transplantation
J.Barret
94-H-0033 Retroviral mediated transfer of cDNA for
Fanconi's anemia type C into hematopoietic\
stem cells of patients with Fanconi's anemia
J.Liu Laura Wisch 301-402-0797
94-H-0010 Evaluation, treatment and training protocol
for patients with bone marrow failure states,
isolated or multi-lineage cytopenias, or
hematologic malignancies
C.Dunbar
86-H-0088 Lymphapheresis of patients with
pancytopenia
N.Young Olga Nunez 301-496-4462
85-H-0087 Clinical course of patients with transfusional
hemochromatosis on deferoxamine
G.Rodgers Beth Link 301-402-3087
84-H-0137 Scientific collaborations with Japan, China
and Thailand
N.Young Olga Nunez 301-496-4462
84-H-0029 Effect of hydroxyurea on fetal hemoglobin
synthesis in patients with sickle cell anemia
G.Rodgers Beth Link 301-402-3087